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- Data Summary
GO Report
Basic Info
| ID | GO:0032587 |
|---|---|
| Name | ruffle membrane |
| Type | Cellular Component |
| No. of Genes in ADHDgene | 12 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 12)
Literature-origin genes (count: 2)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| CLASP2 | cytoplasmic linker associated protein 2 | 3p24.3 | 1(0/0/1) | |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 11p11.2 | 1(0/1/0) |
Genes from other sources (count: 10)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| NF2 | neurofibromin 2 (merlin) | Mapped by PBA pathway | |
| SPATA13 | spermatogenesis associated 13 | Mapped by CNV | IDA[19151759] |
| CFL1 | cofilin 1 (non-muscle) | Mapped by significant region | |
| ADAM17 | ADAM metallopeptidase domain 17 | Mapped by significant region | IDA[14970227] |
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | Mapped by significant region | |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | Mapped by CNV; Mapped by significant region | |
| RPS3 | ribosomal protein S3 | Mapped by significant region | IDA[16814409] |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) | Mapped by significant region | |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | Mapped by PBA pathway | IDA[19043560] |
| APC | adenomatous polyposis coli | Mapped by LD-proxy; Mapped by PBA pathway | IDA[19151759] |