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- Data Summary
GO Report
Basic Info
| ID | GO:0007205 |
|---|---|
| Name | protein kinase C-activating G-protein coupled receptor signaling pathway |
| Type | Biological Process |
| No. of Genes in ADHDgene | 8 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 8)
Literature-origin genes (count: 3)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B | 6q13 | 13(5/8/0) | |
| DGKH | diacylglycerol kinase, eta | 13q13.3 | 1(1/0/0) | IMP[12810723] |
| GRM5 | glutamate receptor, metabotropic 5 | 11q14.3 | 2(1/0/1) |
Genes from other sources (count: 5)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| CHRM1 | cholinergic receptor, muscarinic 1 | Mapped by PBA pathway; Mapped by significant region | TAS[9603968] |
| ADORA2A | adenosine A2a receptor | Mapped by CNV | |
| MS4A2 | membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) | Mapped by PBA pathway; Mapped by significant region | |
| EDNRA | endothelin receptor type A | Mapped by PBA pathway | |
| PLCE1 | phospholipase C, epsilon 1 | Mapped by PBA pathway | NAS[11022048] |