ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0007205
Name protein kinase C-activating G-protein coupled receptor signaling pathway
Type biological process
No. of Genes in ADHDgene  10
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 10)

Literature-origin genes (count: 3)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
DGKH diacylglycerol kinase, eta 13q13.3 2(1/1/0) IMP[12810723]
GRM5 glutamate receptor, metabotropic 5 11q14.3 2(1/0/1) IEA
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 6q13 14(5/9/0) IEA

Genes from other sources Help (count: 7)

Approved Symbol Approved Name Source Evidence[PMID]
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 Mapped by significant region; Mapped by PBA pathway IEA
PICK1 protein interacting with PRKCA 1 Mapped by Literature SNP IDA[10623590]
EDNRA endothelin receptor type A Mapped by PBA pathway IEA
CHRM1 cholinergic receptor, muscarinic 1 Mapped by significant region; Mapped by PBA pathway TAS[9603968]
PLCE1 phospholipase C, epsilon 1 Mapped by PBA pathway NAS[11022048]
DGKG diacylglycerol kinase, gamma 90kDa Mapped by Literature SNP IEA
ADORA2A adenosine A2a receptor Mapped by CNV IEA