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- Data Summary
GO Report
Basic Info
| ID | GO:0007200 |
|---|---|
| Name | phospholipase C-activating G-protein coupled receptor signaling pathway |
| Type | Biological Process |
| No. of Genes in ADHDgene | 12 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 12)
Literature-origin genes (count: 2)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| OPRM1 | opioid receptor, mu 1 | 6q24-q25 | 1(1/0/0) | |
| ADRA1A | adrenergic, alpha-1A-, receptor | 8p21.2 | 3(2/1/0) |
Genes from other sources (count: 10)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| NTSR2 | neurotensin receptor 2 | Mapped by significant region | |
| GPR139 | G protein-coupled receptor 139 | Mapped by significant region | |
| CCKBR | cholecystokinin B receptor | Mapped by CNV; Mapped by PBA pathway | TAS[8455720] |
| CXCR2 | chemokine (C-X-C motif) receptor 2 | Mapped by significant region | IDA[10438939] |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 | Mapped by significant region | TAS[8159738] |
| PLCE1 | phospholipase C, epsilon 1 | Mapped by PBA pathway | IDA[11022047] |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 | Mapped by significant region | TAS[8670200] |
| NPR3 | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | Mapped by significant region | |
| CCKAR | cholecystokinin A receptor | Mapped by CNV | TAS[8343165] |
| LTB4R | leukotriene B4 receptor | Mapped by significant region | TAS[8702478] |