ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0030818
Name	negative regulation of cAMP biosynthetic process
Type	Biological Process
No. of Genes in ADHDgene	7
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 7)

Literature-origin genes (count: 5)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
GRM7	glutamate receptor, metabotropic 7	3p26-p25	1(1/0/0)	IDA[9473604]
GRM8	glutamate receptor, metabotropic 8	7q31.3-q32.1	1(1/0/0)	IDA[11166323]
ADRA2A	adrenergic, alpha-2A-, receptor	10q24-q26	12(4/8/0)	IDA[16531006]
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	6q13	13(5/8/0)	IDA[8882600]
DRD4	dopamine receptor D4	11p15.5	67(49/18/0)	IDA[7512953]

Genes from other sources (count: 2)

Approved Symbol	Approved Name	Source	Evidence[PMID]
EDNRA	endothelin receptor type A	Mapped by PBA pathway
PDE2A	phosphodiesterase 2A, cGMP-stimulated	Mapped by significant region