ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0030818
Name negative regulation of cAMP biosynthetic process
Type biological process
No. of Genes in ADHDgene  7
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 7)

Literature-origin genes (count: 5)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 6q13 14(5/9/0) IDA[8882600]
GRM7 glutamate receptor, metabotropic 7 3p26-p25 3(2/1/0) IDA[9473604]
GRM8 glutamate receptor, metabotropic 8 7q31.3-q32.1 1(1/0/0) IDA[11166323]
DRD4 dopamine receptor D4 11p15.5 67(49/18/0) IDA[7512953]
ADRA2A adrenoceptor alpha 2A 10q25.2 13(4/9/0) IDA[16531006]; ISS

Genes from other sources Help (count: 2)

Approved Symbol Approved Name Source Evidence[PMID]
EDNRA endothelin receptor type A Mapped by PBA pathway IEA
PDE2A phosphodiesterase 2A, cGMP-stimulated Mapped by significant region ISS