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- Data Summary
GO Report
Basic Info
| ID | GO:0030426 |
|---|---|
| Name | growth cone |
| Type | Cellular Component |
| No. of Genes in ADHDgene | 20 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 20)
Literature-origin genes (count: 6)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 9q22.1 | 1(1/0/0) | |
| GSK3B | glycogen synthase kinase 3 beta | 3q13.3 | 1(1/0/0) | |
| NRSN1 | neurensin 1 | 6p22.1 | 1(1/0/0) | |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 6q25 | 1(0/0/1) | |
| SNAP25 | synaptosomal-associated protein, 25kDa | 20p12-p11.2 | 18(13/5/0) | |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 4q21.3-q22 | 1(0/1/0) | IDA[12958153] |
Genes from other sources (count: 14)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| IGHMBP2 | immunoglobulin mu binding protein 2 | Mapped by CNV; Mapped by significant region | |
| DFNB31 | deafness, autosomal recessive 31 | Mapped by significant region | |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | Mapped by significant region | |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | Mapped by significant region | |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | Mapped by PBA pathway | |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 | Mapped by PBA pathway | |
| STX3 | syntaxin 3 | Mapped by significant region | |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 | Mapped by LD-proxy | |
| TSC1 | tuberous sclerosis 1 | Mapped by PBA pathway | |
| MAPT | microtubule-associated protein tau | Mapped by LD-proxy; Mapped by PBA pathway | IDA[8642405] |
| FKBP15 | FK506 binding protein 15, 133kDa | Mapped by significant region | |
| THY1 | Thy-1 cell surface antigen | Mapped by significant region | |
| NCAM1 | neural cell adhesion molecule 1 | Mapped by significant region | |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | Mapped by CNV | IDA[12843239] |