ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0005234
Name	extracellular-glutamate-gated ion channel activity
Type	Molecular Function
No. of Genes in ADHDgene	8
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 8)

Literature-origin genes (count: 5)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
GRIK1	glutamate receptor, ionotropic, kainate 1	21q22	1(0/0/1)
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	12p12	1(1/0/0)
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	16p13.2	3(1/2/0)
GRIK4	glutamate receptor, ionotropic, kainate 4	11q	1(0/1/0)
GRID2	glutamate receptor, ionotropic, delta 2	4q22	1(0/0/1)

Genes from other sources (count: 3)

Approved Symbol	Approved Name	Source	Evidence[PMID]
GRIA4	glutamate receptor, ionotrophic, AMPA 4	Mapped by significant region
GRIN3A	glutamate receptor, ionotropic, N-methyl-D-aspartate 3A	Mapped by significant region
STX1B	syntaxin 1B	Mapped by CNV	TAS[8105537]