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- Data Summary
GO Report
Basic Info
| ID | GO:0007202 |
|---|---|
| Name | activation of phospholipase C activity |
| Type | Biological Process |
| No. of Genes in ADHDgene | 12 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 12)
Literature-origin genes (count: 3)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| NGF | nerve growth factor (beta polypeptide) | 1p13.1 | 2(2/0/0) | |
| ADRBK1 | adrenergic, beta, receptor kinase 1 | 11q13 | 1(0/1/0) | |
| ADRA1A | adrenergic, alpha-1A-, receptor | 8p21.2 | 3(2/1/0) |
Genes from other sources (count: 9)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| LPAR1 | lysophosphatidic acid receptor 1 | Mapped by significant region | TAS[9804623] |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | Mapped by LD-proxy; Mapped by literature SNP | |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | Mapped by CNV | |
| PLCB2 | phospholipase C, beta 2 | Mapped by PBA pathway | TAS[7649993] |
| EDNRA | endothelin receptor type A | Mapped by PBA pathway | TAS[8702836] |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | Mapped by CNV | |
| MS4A2 | membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) | Mapped by PBA pathway; Mapped by significant region | |
| ITK | IL2-inducible T-cell kinase | Mapped by significant region | |
| ADCY4 | adenylate cyclase 4 | Mapped by significant region |