ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0007190
Name activation of adenylate cyclase activity
Type biological process
No. of Genes in ADHDgene  10
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 10)

Literature-origin genes (count: 7)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
DRD1 dopamine receptor D1 5q34-q35 8(5/3/0) IDA[2168520]
DRD5 dopamine receptor D5 4p16.1 22(14/6/2) TAS[9457173]
ADRB2 adrenoceptor beta 2, surface 5q31-q32 2(1/1/0) IDA[15123695]
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 9q22.1 1(1/0/0) TAS
ADRB1 adrenoceptor beta 1 10q25.3 2(0/2/0) TAS[10212248]
ADRB3 adrenoceptor beta 3 8p12 2(0/2/0) IDA[15123695]
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 18p11.22-p11.21 1(1/0/0) IEA

Genes from other sources Help (count: 3)

Approved Symbol Approved Name Source Evidence[PMID]
GIPR gastric inhibitory polypeptide receptor Mapped by LD-proxy TAS[7589426]
ADORA2A adenosine A2a receptor Mapped by CNV TAS
EDNRA endothelin receptor type A Mapped by PBA pathway TAS[8702836]