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- Data Summary
GO Report
Basic Info
| ID | GO:0007265 |
|---|---|
| Name | Ras protein signal transduction |
| Type | Biological Process |
| No. of Genes in ADHDgene | 15 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 15)
Literature-origin genes (count: 2)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| ADRA2A | adrenergic, alpha-2A-, receptor | 10q24-q26 | 12(4/8/0) | TAS[8226727] |
| NGF | nerve growth factor (beta polypeptide) | 1p13.1 | 2(2/0/0) |
Genes from other sources (count: 13)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| MAPK3 | mitogen-activated protein kinase 3 | Mapped by CNV | |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | Mapped by LD-proxy | NAS[9674433] |
| MAPK1 | mitogen-activated protein kinase 1 | Mapped by LD-proxy | |
| RREB1 | ras responsive element binding protein 1 | Mapped by CNV | TAS[8816445] |
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | Mapped by CNV | TAS[8798523] |
| PLCE1 | phospholipase C, epsilon 1 | Mapped by PBA pathway | TAS[11022048] |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | Mapped by significant region | |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | Mapped by LD-proxy; Mapped by literature SNP | |
| PLD1 | phospholipase D1, phosphatidylcholine-specific | Mapped by PBA pathway | TAS[10848592] |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) | Mapped by significant region | NAS[10918068] |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | Mapped by CNV | NAS[9575347] |
| BRAP | BRCA1 associated protein | Mapped by LD-proxy | IDA[14724641] |
| GRAP | GRB2-related adaptor protein | Mapped by significant region | TAS[8647802] |