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- Data Summary
GO Report
Basic Info
| ID | GO:0030165 |
|---|---|
| Name | PDZ domain binding |
| Type | Molecular Function |
| No. of Genes in ADHDgene | 13 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 13)
Literature-origin genes (count: 5)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| GRID2 | glutamate receptor, ionotropic, delta 2 | 4q22 | 1(0/0/1) | |
| GRM7 | glutamate receptor, metabotropic 7 | 3p26-p25 | 1(1/0/0) | NAS[12052533] |
| LIN7C | lin-7 homolog C (C. elegans) | 11p14 | 1(1/0/0) | |
| ADRB1 | adrenergic, beta-1-, receptor | 10q24-q26 | 2(0/2/0) | IPI[11526121] |
| PARK2 | parkinson protein 2, E3 ubiquitin protein ligase (parkin) | 6q25.2-q27 | 1(1/0/0) | IPI[17512523] |
Genes from other sources (count: 8)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| GJA1 | gap junction protein, alpha 1, 43kDa | Mapped by significant region | |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | Mapped by CNV | ISS[9459447] |
| ADAM17 | ADAM metallopeptidase domain 17 | Mapped by significant region | IPI[12207026] |
| SNTG2 | syntrophin, gamma 2 | Mapped by CNV | IPI[17292328] |
| CADM1 | cell adhesion molecule 1 | Mapped by significant region | ISS[12826663] |
| SLC22A12 | solute carrier family 22 (organic anion/urate transporter), member 12 | Mapped by significant region | IPI[15304510] |
| LPAR1 | lysophosphatidic acid receptor 1 | Mapped by significant region | |
| FZD4 | frizzled family receptor 4 | Mapped by significant region | IPI[19388021] |