ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs7162879 dbSNP Ensembl
Location	Chr15:55978441(Fwd)
Variant Alleles	T/A
Ancestral Allele	T
Functional Annotation	downstream_gene_variant; intron_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000561155) intron_variant(ENST00000389286)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Wigg KG, 2008	T/A		TDT P-value=0.018, X²=5.555 TDT P-value=0.018, X²=5.555	was significantly associated to ADHD was significantly associated to ADHD	Significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
PRTG	protogenin	15q21.3	1(1/0/0)

Genes from other sources (count: 0)

SNPs in LD with rs7162879 (count: 41) View in gBrowse (chr15:55945381..56062580 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 5)

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs11854213	downstream_gene_variant; synonymous_variant; upstream_gene_variant	1(0/1/0)	0.855[CHB]
rs2414424	intron_variant	1(1/0/0)	0.907[CHB]; 1.0[JPT]
rs4774800	intron_variant	1(0/1/0)	0.865[CHB]
rs12438177	intron_variant	1(0/1/0)	0.864[CHB]
rs9920546	downstream_gene_variant; intron_variant	1(0/1/0)	0.931[YRI]

LD-proxies (count: 36)

rs_ID	Functional Annotation	r²[population]
rs12442771	downstream_gene_variant; intron_variant; upstream_gene_variant	0.855[CHB]
rs2414427	intron_variant	0.907[CHB]; 0.952[JPT]
rs10851589	intron_variant	0.955[CHB]
rs7181471		0.866[CHB]; 0.86[JPT]
rs12903822	intron_variant	0.813[CHB]
rs17238367		0.867[YRI]
rs9920246	downstream_gene_variant; intron_variant	0.87[CHB]
rs2414426	intron_variant	0.907[CHB]; 0.952[JPT]
rs7171318	downstream_gene_variant; intron_variant	0.955[CHB]
rs4377101	intron_variant	0.809[CHB]
rs7178379	3_prime_UTR_variant; intron_variant	0.955[CHB]
rs8032175	intron_variant	0.932[YRI]
rs10518817	intron_variant	0.955[CHB]
rs6493814	downstream_gene_variant; intron_variant; upstream_gene_variant	0.855[CHB]
rs16976467	downstream_gene_variant; intron_variant; upstream_gene_variant	0.931[YRI]
rs2414431	downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant	0.809[CHB]; 0.817[JPT]
rs12591246	intron_variant	0.955[CHB]; 1.0[JPT]
rs4774802	intron_variant	0.808[CHB]; 0.905[JPT]
rs7163167	upstream_gene_variant	0.803[CHB]
rs2118781	downstream_gene_variant; intron_variant; upstream_gene_variant	0.903[CHB]
rs6493806	downstream_gene_variant; intron_variant	0.867[YRI]
rs12373006	downstream_gene_variant; intron_variant; upstream_gene_variant	1.0[CEU]; 0.903[CHB]
rs8025445	downstream_gene_variant; intron_variant	0.855[CHB]
rs9920076	downstream_gene_variant; intron_variant	0.872[CHB]
rs7182733	intron_variant; upstream_gene_variant	0.855[CHB]
rs8037136	downstream_gene_variant; intron_variant	0.82[CHB]
rs1371056	intron_variant	0.817[JPT]
rs2008336	intron_variant	0.819[CHB]; 0.861[JPT]
rs7162504	intron_variant	0.932[YRI]
rs12594642	intron_variant	0.817[JPT]
rs7179697	intron_variant; nc_transcript_variant; upstream_gene_variant	0.932[YRI]
rs1530087	intron_variant	0.824[JPT]
rs8027291	intron_variant	0.928[YRI]
rs7181212	intron_variant	0.807[CHB]; 0.805[JPT]
rs16976450	intron_variant	0.813[CHB]
rs16976472	downstream_gene_variant; intron_variant	1.0[CEU]; 0.955[CHB]; 1.0[JPT]; 1.0[YRI]