ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs2414424 dbSNP Ensembl
Location	Chr15:56000063(Fwd)
Variant Alleles	C/T
Ancestral Allele	C
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000389286)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Wigg KG, 2008	A/G		TDT P-value=0.005, X²=8.067; P-value=0.046 after ...... TDT P-value=0.005, X²=8.067; P-value=0.046 after permutation testing More...	was significantly associated to ADHD was significantly associated to ADHD	Significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
PRTG	protogenin	15q21.3	1(1/0/0)

Genes from other sources (count: 0)

SNPs in LD with rs2414424 (count: 40) View in gBrowse (chr15:55944517..56063040 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 4)

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs4774800	intron_variant	1(0/1/0)	0.859[CHB]
rs12438177	intron_variant	1(0/1/0)	0.85[CHB]
rs11854213	downstream_gene_variant; synonymous_variant; upstream_gene_variant	1(0/1/0)	0.863[CHB]
rs7162879	downstream_gene_variant; intron_variant	1(1/0/0)	0.907[CHB]; 1.0[JPT]

LD-proxies (count: 36)

rs_ID	Functional Annotation	r²[population]
rs2414431	downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant	0.821[CHB]; 0.817[JPT]
rs12591246	intron_variant	1.0[CEU]; 0.953[CHB]; 1.0[JPT]; 1.0[YRI]
rs11858195	intron_variant	0.811[GIH]
rs9920246	downstream_gene_variant; intron_variant	0.907[CHB]
rs572531	downstream_gene_variant; intron_variant	0.904[MEX]
rs4377101	intron_variant	0.821[CHB]
rs7163167	upstream_gene_variant	0.853[CHB]; 0.823[CHD]
rs2414433		0.858[CHB]; 0.802[CHD]; 0.903[MEX]; 0.814[TSI]
rs2118781	downstream_gene_variant; intron_variant; upstream_gene_variant	0.859[CHB]
rs4774802	intron_variant	0.907[CHB]; 0.843[CHD]; 0.905[JPT]
rs1371056	intron_variant	1.0[CEU]; 0.977[GIH]; 0.817[JPT]; 0.951[MEX]; 0.967[TSI]
rs6493814	downstream_gene_variant; intron_variant; upstream_gene_variant	0.863[CHB]
rs7171318	downstream_gene_variant; intron_variant	0.953[CHB]
rs9920076	downstream_gene_variant; intron_variant	0.801[CEU]; 0.859[CHB]
rs8025445	downstream_gene_variant; intron_variant	0.863[CHB]
rs16976525		0.904[MEX]; 0.875[TSI]
rs2414426	intron_variant	1.0[CEU]; 1.0[CHB]; 0.976[CHD]; 0.977[GIH]; 0.952[JPT]; 0.951[MEX]; 1.0[TSI]
rs7181471		0.951[CHB]; 0.855[JPT]; 0.858[MEX]
rs12373006	downstream_gene_variant; intron_variant; upstream_gene_variant	0.907[CHB]; 0.814[CHD]; 0.888[GIH]; 0.816[MEX]
rs1814329	downstream_gene_variant	0.858[CHB]
rs6493809	intron_variant	0.863[CHB]
rs8037136	downstream_gene_variant; intron_variant	0.821[CHB]; 0.817[JPT]
rs12594642	intron_variant	1.0[CEU]; 0.934[GIH]; 0.817[JPT]; 0.951[MEX]; 0.968[TSI]
rs2414427	intron_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 0.976[CHD]; 1.0[GIH]; 0.952[JPT]; 1.0[LWK]; 1.0[MEX]; 1.0[MKK]; 0.968[TSI]; 1.0[YRI]
rs1530087	intron_variant	0.801[CEU]; 0.817[JPT]
rs10518817	intron_variant	0.801[CEU]; 0.953[CHB]
rs2008336	intron_variant	0.907[CHB]; 0.855[JPT]
rs16976472	downstream_gene_variant; intron_variant	0.953[CHB]; 1.0[JPT]
rs7359255		0.858[CHB]
rs12442771	downstream_gene_variant; intron_variant; upstream_gene_variant	0.863[CHB]
rs7178379	3_prime_UTR_variant; intron_variant	0.953[CHB]
rs7181212	intron_variant	0.808[CHB]; 0.844[JPT]
rs10851589	intron_variant	0.801[CEU]; 0.953[CHB]
rs7182733	intron_variant; upstream_gene_variant	0.863[CHB]
rs16976450	intron_variant	0.812[CHB]; 0.856[MEX]
rs12903822	intron_variant	0.812[CHB]; 0.836[CHD]