ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs11854213 dbSNP Ensembl
Location	Chr15:55970041(Fwd)
Variant Alleles	A/G
Ancestral Allele	A
Functional Annotation	downstream_gene_variant; synonymous_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000559842) synonymous_variant(ENST00000389286) upstream_gene_variant(ENST00000561155; ENST00000561465)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Wigg KG, 2008	T/C		TDT P-value=0.773, X²=0.083 TDT P-value=0.773, X²=0.083	no evidence for association no evidence for association	Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
PRTG	protogenin	15q21.3	1(1/0/0)

Genes from other sources (count: 0)

SNPs in LD with rs11854213 (count: 38) View in gBrowse (chr15:55943542..56044971 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 6)

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs16976466	missense_variant; nc_transcript_variant; non_coding_exon_variant; splice_region_variant; upstream_gene_variant	1(0/1/0)	1.0[ASW]; 0.907[CEU]; 1.0[GIH]; 1.0[LWK]; 1.0[MEX]; 1.0[MKK]; 0.952[TSI]; 1.0[YRI]
rs2414424	intron_variant	1(1/0/0)	0.863[CHB]
rs12438177	intron_variant	1(0/1/0)	0.856[CHB]; 0.805[JPT]; 1.0[YRI]
rs4774800	intron_variant	1(0/1/0)	0.823[CHB]; 0.818[JPT]
rs492363	downstream_gene_variant; intron_variant	1(0/1/0)	0.86[JPT]
rs7162879	downstream_gene_variant; intron_variant	1(1/0/0)	0.855[CHB]

LD-proxies (count: 32)

rs_ID	Functional Annotation	r²[population]
rs16976450	intron_variant	0.863[CHB]; 0.909[JPT]
rs7163167	upstream_gene_variant	0.903[CHB]; 0.833[CHD]
rs12903822	intron_variant	0.863[CHB]; 0.865[CHD]; 0.867[JPT]
rs7181212	intron_variant	0.841[CHB]
rs12373006	downstream_gene_variant; intron_variant; upstream_gene_variant	0.952[CHB]; 0.88[CHD]; 0.909[JPT]
rs2414431	downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant	0.854[CHB]; 0.813[CHD]
rs7182733	intron_variant; upstream_gene_variant	0.806[CHB]
rs9920246	downstream_gene_variant; intron_variant	0.821[CHB]; 0.909[JPT]
rs572531	downstream_gene_variant; intron_variant	0.826[JPT]
rs2414427	intron_variant	0.863[CHB]
rs6493809	intron_variant	0.902[CHB]; 0.813[CHD]
rs10518817	intron_variant	0.906[CHB]; 0.909[JPT]
rs7171318	downstream_gene_variant; intron_variant	0.906[CHB]; 0.909[JPT]
rs16976472	downstream_gene_variant; intron_variant	0.906[CHB]
rs10851589	intron_variant	0.906[CHB]; 0.86[JPT]
rs12591246	intron_variant	0.812[CHB]
rs12442771	downstream_gene_variant; intron_variant; upstream_gene_variant	0.806[CHB]
rs2118781	downstream_gene_variant; intron_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 0.953[JPT]; 0.865[MEX]; 1.0[TSI]
rs2414426	intron_variant	0.863[CHB]
rs7359255		0.812[CHB]
rs1014551	intron_variant	1.0[ASW]; 0.828[CEU]; 0.939[GIH]; 0.823[LWK]; 0.865[MEX]; 1.0[YRI]
rs7178379	3_prime_UTR_variant; intron_variant	0.906[CHB]; 0.86[JPT]
rs8025445	downstream_gene_variant; intron_variant	1.0[CHB]; 0.86[CHD]; 0.953[JPT]
rs2414433		0.812[CHB]
rs7181471		0.814[CHB]
rs8037136	downstream_gene_variant; intron_variant	0.854[CHB]
rs4377101	intron_variant	0.854[CHB]; 0.813[CHD]
rs2008336	intron_variant	0.855[CHB]
rs1814329	downstream_gene_variant	0.812[CHB]
rs9920076	downstream_gene_variant; intron_variant	0.823[CHB]; 0.909[JPT]
rs4774802	intron_variant	0.855[CHB]
rs6493814	downstream_gene_variant; intron_variant; upstream_gene_variant	0.806[CHB]