ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs362987 dbSNP Ensembl
Location chr20:10277452(Fwd)
Variant Alleles A/C
Ancestral Allele C
Functional Annotation downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant.
Consequence to Transcript downstream_gene_variant(ENST00000430336)
intron_variant(ENST00000254976; ENST00000304886; ENST00000421143; ENST00000453544)
nc_transcript_variant(ENST00000421143; ENST00000453544; ENST00000495883)
non_coding_exon_variant(ENST00000495883)
No. of Studies 5 (significant: 1; non-significant: 4; trend: 0)
Source Literature-origin

SNP related studies (count: 5)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Ilott NE, 2010 QTDT AT P-value=0.84, X2=0.04, df=1, QTDT AW P-va...... QTDT AT P-value=0.84, X2=0.04, df=1, QTDT AW P-value=0.79, X2=0.07, df=1 at age 2; QTDT AT P-value=0.91, X2=0.04, df=1, QTDT AW P-value=0.39, X2=0.39, df=1 at age 3 More... no significant association no significant association Non-significant
Kim JW, 2007 A/C C Combined TDT P-value=0.25 (OR=1.11); Single marker analysis ...... Combined TDT P-value=0.25 (OR=1.11); Single marker analysis FBAT P-value=0.699; Exploratory analyses FBAT P-value=1 for co-morbid CD, P-value=0.169 for co-morbid MDD, P-value=0.723 for co-morbid BD More... No association was found between ADHD or co-morbidities of A...... No association was found between ADHD or co-morbidities of ADHD and this SNP More... Non-significant
Feng Y, 2005(b) A/C allelic TDT P-value=0.249, X2=1.328 in Irvine sam...... allelic TDT P-value=0.249, X2=1.328 in Irvine sample; allelic TDT P-value=0.039, X2=4.269 in Toronto sample; TDT P-value=0.631, X2(1df)=0.231 in the Toronto sample by Inattentive subtype; TDT P-value=0.819, X2(1df)=0.053 in the Toronto sample by Hyperactive/impulsive subtype; TDT P-value=0.016, X2(1df)=5.841 in the Toronto sample by Combined subtype More... there was significant evidence for biased transmission in th...... there was significant evidence for biased transmission in the Toronto sample; TDT test was not significant in the Irvine sample; the observed evidence for biased transmission was not significant in the inattentive or hyperactive/impulsive subtype, but significant in the combined subtype in the Toronto sample More... Significant
Brookes K, 2006 A/C UNPHASED TDT P-value=0.906; WHAP TDT P-value=0.926 UNPHASED TDT P-value=0.906; WHAP TDT P-value=0.926 no significant association was observed no significant association was observed Non-significant
Gizer IR, 2009 Meta-analysis model: Random: OR=1, 95% CI=0.84-1.18, P-value...... Meta-analysis model: Random: OR=1, 95% CI=0.84-1.18, P-value=0.488; Q-statistic: P-value=0.099, I2=49 More... no evidence to suggest an association between this polymorph...... no evidence to suggest an association between this polymorphisms and ADHD More... Non-significant

SNP related genes (count: 2)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 1)


SNPs in LD with rs362987 (count: 3) View in gBrowse (chr20:10253082..10277452 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 3)