ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs362549 dbSNP Ensembl
Location chr20:10269890(Fwd)
Variant Alleles A/G
Ancestral Allele G
Functional Annotation intron_variant; nc_transcript_variant.
Consequence to Transcript intron_variant(ENST00000254976; ENST00000304886; ENST00000421143; ENST00000430336; ENST00000453544)
nc_transcript_variant(ENST00000421143; ENST00000453544)
No. of Studies 3 (significant: 2; non-significant: 1; trend: 0)
Source Literature-origin

SNP related studies (count: 3)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Feng Y, 2005(b) A/G allelic TDT P-value=0.225, X2=1.473 in Irvine sam...... allelic TDT P-value=0.225, X2=1.473 in Irvine sample; allelic TDT P-value=0.012, X2=6.352 in Toronto sample; TDT P-value=0.612, X2(1df)=0.257 in the Toronto sample by Inattentive subtype; TDT P-value=0.491, X2(1df)=0.474 in the Toronto sample by Hyperactive/impulsive subtype; TDT P-value=0.008, X2(1df)=7.042 in the Toronto sample by Combined subtype More... there was significant evidence for biased transmission in th...... there was significant evidence for biased transmission in the Toronto sample; TDT test was not significant in the Irvine sample; the observed evidence for biased transmission was not significant in the inattentive or hyperactive/impulsive subtype, but significant in the combined subtype in the Toronto sample More... Significant
Kim JW, 2007 G/A A Combined TDT P-value=0.11 (OR=1.16); Single marker analysis ...... Combined TDT P-value=0.11 (OR=1.16); Single marker analysis FBAT P-value=0.466; Exploratory analyses FBAT P-value=0.892 for co-morbid CD, P-value=0.429 for co-morbid MDD, P-value=0.465 for co-morbid BD More... No association was found between ADHD or co-morbidities of A...... No association was found between ADHD or co-morbidities of ADHD and this SNP More... Non-significant
Zhang HY, 2011 A/G TDT P-value=0.0047, X2=8.00 for inattentive subty...... TDT P-value=0.0047, X2=8.00 for inattentive subtype, TDT P-value=0.0423, X2=4.122 for ADHD-C subtype; Cross-tab P-value=0.0247, X2=5.0467 for ADHD-I subtype, Cross-tab P-value=0.0955, X2=2.779 for ADHD-C subtype More... showed surprisingly a statistical significant trend of biase...... showed surprisingly a statistical significant trend of biased transmission in ADHD-IA subtype and ADHD-C subtype. By correcting with cross-tab analysis, it still remains statistical significantin in ADHD-IA subtype, but that in ADHD-C subtype showed only a trend but not significant. More... Significant

SNP related genes (count: 2)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 1)


SNPs in LD with rs362549 (count: 2) View in gBrowse (chr20:10253082..10269890 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 2)