ADHDgene Database
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Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs2242447 dbSNP Ensembl
Location Chr16:55735912(Fwd)
Variant Alleles C/T
Ancestral Allele C
Functional Annotation intron_variant.
Consequence to Transcript intron_variant(ENST00000567238; ENST00000566163; ENST00000568943; ENST00000561820; ENST00000414754; ENST00000574918; ENST00000219833; ENST00000379906)
No. of Studies 6 (significant: 1; non-significant: 5; trend: 0)
Source Literature-origin

SNP related studies (count: 6)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Xu X, 2005(a) TDT P-value=0.07, OR=1.17 TDT P-value=0.07, OR=1.17 no evidence for association no evidence for association Non-significant
Gizer IR, 2009 Meta-analysis model: Random: OR=1.04, 95% CI=0.91-1.19, two-...... Meta-analysis model: Random: OR=1.04, 95% CI=0.91-1.19, two-tailed P-value=0.589; Q-statistic: P-value=0.319, I2=14 More... no evidence to suggest an association between this polymorph...... no evidence to suggest an association between this polymorphisms and ADHD More... Non-significant
Hawi, Z., 2012 T:C T P-value=0.0065*, X2=7.42, OR=1.47, 95% CI=1.11-1....... P-value=0.0065*, X2=7.42, OR=1.47, 95% CI=1.11-1.94 More... Nominal associations between ADHD and the marker was observe...... Nominal associations between ADHD and the marker was observed. However, the association did not remain significant after adjusting the p values using 10,000 permutations. More... Significant
Sengupta, S. M., 2012 T/C P-value=0.25, Z statistic (allele 1)=1.15 P-value=0.25, Z statistic (allele 1)=1.15 No significant association was found in this study. No significant association was found in this study. Non-significant
Brookes K, 2006 A/G UNPHASED TDT P-value=0.703; WHAP TDT P-value=0.912 UNPHASED TDT P-value=0.703; WHAP TDT P-value=0.912 no significant association was observed no significant association was observed Non-significant
Ilott NE, 2010 QTDT AT P-value=0.27, X2=1.23, df=1, QTDT AW P-va...... QTDT AT P-value=0.27, X2=1.23, df=1, QTDT AW P-value=0.31, X2=1.03, df=1 at age 2; QTDT AT P-value=0.18, X2=3.56, df=1, QTDT AW P-value=0.16, X2=2.01, df=1 at age 3 More... no significant association no significant association Non-significant

SNP related genes (count: 2)

Literature-origin genes (count: 2)

Genes from other sources Help (count: 0)


SNPs in LD with rs2242447 (count: 4) View in gBrowse (chr16:55735912..55782924 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 4)

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014