ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs1611115 dbSNP Ensembl
Location chr9:136500515(Fwd)
Variant Alleles T/C
Ancestral Allele C
Functional Annotation upstream_gene_variant.
Consequence to Transcript upstream_gene_variant(ENST00000263611; ENST00000393056; ENST00000564021)
No. of Studies 7 (significant: 2; non-significant: 5; trend: 0)
Source Literature-origin

SNP related studies (count: 7)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Bhaduri N, 2006 (b) C/T allelic HHRR P-value=1.0, X2=0.0; allelic TDT P-v...... allelic HHRR P-value=1.0, X2=0.0; allelic TDT P-value=1.0, X2=0.0; RR=1.0 (for A1 and A2) More... both HHRR and TDT analysis revealed lack of association betw...... both HHRR and TDT analysis revealed lack of association between ADHD and transmission of the T allele More... Non-significant
Hess C, 2009 C/T Phenotypic analysis: CC vs. CT vs. TT, P-value=0.070; C+ vs....... Phenotypic analysis: CC vs. CT vs. TT, P-value=0.070; C+ vs. C-, P-value=0.045 More... No association was observed when comparing the DBH C-1021T f...... No association was observed when comparing the DBH C-1021T full genotype distributions of adult ADHD patients and controls; howerer, a significant association was found between the rare TT genotype and ADHD. More... Significant
Hawi, Z., 2012 C:T T P-value=0.9356, X2=0.01, OR=1.01, 95% CI=0.74-1.3...... P-value=0.9356, X2=0.01, OR=1.01, 95% CI=0.74-1.39 More... The marker did not show significant association with ADHD. The marker did not show significant association with ADHD. Non-significant
Bhaduri N, 2010 C:T allelic frequencies P-value=0.4, X2=0.65; genotyp...... allelic frequencies P-value=0.4, X2=0.65; genotypic frequencies P-value=0.72, X2=0.65; HHRR P-value=0.88, OR=1.04, X2=0.02, TDT P-value=0.88, RR=1.05, X2=0.02 for overall transmission; HHRR P-value=0.69, OR=0.85, X2=0.16, TDT P-value=0.65, RR=1.22, X2=0.2 for paternal transmission; HHRR P-value=0.55, OR=1.26, X2=0.35, TDT P-value=0.55, RR=1.27, X2=0.36 for maternal transmission More... no significant association with ADHD no significant association with ADHD Non-significant
Kwon, H. J.,2013 C/T allelic chi-square tests, P-value=0.034 (OR=0.64; 95%CI=0.42...... allelic chi-square tests, P-value=0.034 (OR=0.64; 95%CI=0.42-0.97; X2=2.11); genotypic chi-square tests, P-value=0.029 (OR=0.58; 95%CI=0.35-0.95; X2=2.18). More... There was a signi?cant correlation among the frequencies of ...... There was a signi?cant correlation among the frequencies of rs1611115 of the alleles of DBH, but the ?nal conclusions are not de?nite. Follow-up studies with larger patient or pure subgroups are expected. More... Significant
Gizer IR, 2009 Meta-analysis model: Random: OR=1.05, 95% CI=0.83-1.33, two-...... Meta-analysis model: Random: OR=1.05, 95% CI=0.83-1.33, two-tailed P-value=0.692; Q-statistic: P-value=0.189, I2=37 More... no evidence to suggest an association between this polymorph...... no evidence to suggest an association between this polymorphisms and ADHD More... Non-significant
Das M, 2011 C/T ETDT P-value=0.49, X2(1df)=0.47, RR=1; allelic fr...... ETDT P-value=0.49, X2(1df)=0.47, RR=1; allelic frequencies COCAPHASE P-value=0.09, X2=2.8 for C; ETDT P-value=0.49, X2(1df)=0.47, RR=0.83; allelic frequencies COCAPHASE P-value=0.09, X2=2.8 for T More... no significant association was noticed by case-control or fa...... no significant association was noticed by case-control or family-based association analyses More... Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 0)


SNPs in LD with rs1611115 (count: 1) View in gBrowse (chr9:136500515..136502328 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 1)