Variant Name |
Allele Change |
Risk Allele |
Statistical Values |
Author Comments |
Result of Statistical Analysis |
SLC6A3 intron8 VNTR |
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ETDT P-value=0.1, X2(1df)=2.77, RR=7.71e+007; all......
ETDT P-value=0.1, X2(1df)=2.77, RR=7.71e+007; allelic frequencies COCAPHASE P-value=0.8, X2=0.07 for 11R; ETDT P-value=0.53, X2(1df)=0.4, RR=0.53; allelic frequencies COCAPHASE P-value=0.056, X2=3.64 for 10R; ETDT P-value=0.31, X2(1df)=1.02, RR=1.8; allelic frequencies COCAPHASE P-value=0.28, X2=1.17 for 9R; ETDT P-value=0.34, X2(1df)=0.89, RR=0.81; allelic frequencies COCAPHASE P-value=0.002, X2=9.59 for 6R; ETDT P-value=0.53, X2(1df)=0.4, RR=1; allelic frequencies COCAPHASE P-value=0.02, X2=5.49 for 5R; allelic frequencies COCAPHASE P-value=0.29, X2=1.13 for 7R
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the data was statistically not significant in either case-control or family-based analysis for 11R, 10R, 9R and 7R; the 6R allele showed significantly lower frequency in ADHD case group but ETDT analysis failed to show any bias in transmission; the 5R allele showed significantly higher occurrence in ADHD case group but ETDT analysis failed to show any bias in transmission |
Significant
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SLC6A3 3'-UTR VNTR |
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ETDT P-value=1, X2(1df)=0, RR=1; allelic frequenc......
ETDT P-value=1, X2(1df)=0, RR=1; allelic frequencies COCAPHASE P-value=0.99, X2=0.0001 for 11R; ETDT P-value=0.08, X2(1df)=3.1, RR=0.84; allelic frequencies COCAPHASE P-value=0.34, X2=0.92 for 10R; ETDT P-value=0.14, X2(1df)=2.19, RR=1.35; allelic frequencies COCAPHASE P-value=0.61, X2=0.26 for 9R; ETDT P-value=1, X2(1df)=0, RR=0.85; allelic frequencies COCAPHASE P-value=0.83, X2=0.04 for 8R; ETDT P-value=0.25, X2(1df)=1.33, RR=2.25; allelic frequencies COCAPHASE P-value=0.02, X2=5.6 for 7R
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the data was statistically not significant in either case-control or family-based analysis for 8R, 9R, 10R and 11R; no significant contribution was noticed by family-based analysis; case-control analysis revealed statistically significant difference for the 7R |
Significant
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MAOA promoter VNTR |
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ETDT P-value=0.63, X2(1df)=0.23, RR=1; allelic fr......
ETDT P-value=0.63, X2(1df)=0.23, RR=1; allelic frequencies COCAPHASE P-value=0.57, X2=0.33 for 3R; ETDT P-value=0.63, X2(1df)=0.23, RR=0.86; allelic frequencies COCAPHASE P-value=0.57, X2=0.33 for 4R
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the data was statistically not significant in either case-control or family-based analysis |
Non-significant
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DRD4 exon3 VNTR |
2-7R |
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ETDT P-value=0.7, X2(1df)=0.14, RR=1; allelic fre......
ETDT P-value=0.7, X2(1df)=0.14, RR=1; allelic frequencies COCAPHASE P-value=0.83, X2=0.04 for 2R. ETDT P-value=1, X2(1df)=0, RR=1.1; allelic frequencies COCAPHASE P-value=0.81, X2=0.06 for 3R. ETDT P-value=0.47, X2(1df)=0.51, RR=1.1; allelic frequencies COCAPHASE P-value=0.92, X2=0.008 for 4R. ETDT P-value=0.31, X2(1df)=1.05, RR=0.42; allelic frequencies COCAPHASE P-value=0.38, X2=0.77 for 5R. ETDT P-value=0.1, X2(1df)=2.64, RR=2.27; allelic frequencies COCAPHASE P-value=0.16, X2=2.01 for 6R. ETDT P-value=0.41, X2(1df)=0.68, RR=2.22; allelic frequencies COCAPHASE P-value=0.55, X2=0.35 for 7R.
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no significant contribution was noticed by either case-control or family-based analysis for 2-5R; no significant contribution was noticed by case-control analysis; ETDT analysis revealed higher transmission from parents to ADHD probands with higher relative risk for 6R and 7R. |
Non-significant
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