ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0004725
Name	protein tyrosine phosphatase activity
Type	Molecular Function
No. of Genes in ADHDgene	19
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 19)

Literature-origin genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
PTPRJ	protein tyrosine phosphatase, receptor type, J	11p11.2	1(0/1/0)	IDA[10821867]; IMP[9780142]
PTPRG	protein tyrosine phosphatase, receptor type, G	3p21-p14	1(0/0/1)	IDA[19167335]

Genes from other sources (count: 17)

Approved Symbol	Approved Name	Source	Evidence[PMID]
CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)	Mapped by significant region	IDA[9367992]
PTPN14	protein tyrosine phosphatase, non-receptor type 14	Mapped by literature SNP
PTPRK	protein tyrosine phosphatase, receptor type, K	Mapped by CNV; Mapped by significant region	IDA[8663237]
DUSP12	dual specificity phosphatase 12	Mapped by CNV
TPTE2	transmembrane phosphoinositide 3-phosphatase and tensin homolog 2	Mapped by significant region
MTMR2	myotubularin related protein 2	Mapped by significant region
MDP1	magnesium-dependent phosphatase 1	Mapped by significant region
EYA4	eyes absent homolog 4 (Drosophila)	Mapped by significant region
PTPMT1	protein tyrosine phosphatase, mitochondrial 1	Mapped by LD-proxy
CDC25B	cell division cycle 25 homolog B (S. pombe)	Mapped by CNV	TAS[9188863]
PTPN3	protein tyrosine phosphatase, non-receptor type 3	Mapped by significant region	IDA[19167335]
DUSP2	dual specificity phosphatase 2	Mapped by LD-proxy
PTPDC1	protein tyrosine phosphatase domain containing 1	Mapped by significant region
SSH3	slingshot homolog 3 (Drosophila)	Mapped by significant region
PTP4A1	protein tyrosine phosphatase type IVA, member 1	Mapped by significant region	NAS[10569806]
UBASH3B	ubiquitin associated and SH3 domain containing B	Mapped by significant region
DUSP14	dual specificity phosphatase 14	Mapped by CNV