ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0002092
Name	positive regulation of receptor internalization
Type	Biological Process
No. of Genes in ADHDgene	7
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 7)

Literature-origin genes (count: 5)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
ARRB2	arrestin, beta 2	17p13	1(1/0/0)
NTF3	neurotrophin 3	12p13	3(1/2/0)
VEGFA	vascular endothelial growth factor A	6p12	1(0/1/0)
DRD2	dopamine receptor D2	11q22-q23	10(3/7/0)
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	7q21	1(0/0/1)	IDA[11526121]

Genes from other sources (count: 2)

Approved Symbol	Approved Name	Source	Evidence[PMID]
GREM1	gremlin 1	Mapped by CNV; Mapped by significant region	ISS[9660951]
AHI1	Abelson helper integration site 1	Mapped by significant region