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- Data Summary
GO Report
Basic Info
| ID | GO:0048015 |
|---|---|
| Name | phosphatidylinositol-mediated signaling |
| Type | Biological Process |
| No. of Genes in ADHDgene | 16 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 16)
Literature-origin genes (count: 2)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| GSK3B | glycogen synthase kinase 3 beta | 3q13.3 | 1(1/0/0) | |
| NGF | nerve growth factor (beta polypeptide) | 1p13.1 | 2(2/0/0) |
Genes from other sources (count: 14)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 | Mapped by significant region | |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | Mapped by significant region | |
| PIK3C3 | phosphoinositide-3-kinase, class 3 | Mapped by significant region | |
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | Mapped by LD-proxy | NAS[15504738] |
| GAB2 | GRB2-associated binding protein 2 | Mapped by significant region | |
| FEN1 | flap structure-specific endonuclease 1 | Mapped by LD-proxy; Mapped by literature SNP; Mapped by significant region | NAS[15504738] |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | Mapped by significant region | |
| GSN | gelsolin | Mapped by PBA pathway; Mapped by significant region | |
| BAD | BCL2-associated agonist of cell death | Mapped by significant region | |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | Mapped by significant region | NAS[15504738] |
| PLCH1 | phospholipase C, eta 1 | Mapped by PBA pathway | IDA[15702972] |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha | Mapped by CNV | |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | Mapped by significant region | |
| PI4KAP1 | phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1 | Mapped by CNV |