ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0006302
Name double-strand break repair
Type biological process
No. of Genes in ADHDgene  14
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 14)

Literature-origin genes (count: 2)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) 2p23 1(1/0/0) IMP[19261748]
TDP2 tyrosyl-DNA phosphodiesterase 2 6p22.3-p22.1 1(0/1/0) IDA[19794497]; IMP

Genes from other sources Help (count: 12)

Approved Symbol Approved Name Source Evidence[PMID]
TP53BP1 tumor protein p53 binding protein 1 Mapped by Literature SNP TAS
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) Mapped by CNV IEA
CDCA5 cell division cycle associated 5 Mapped by significant region IMP[17349791]
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) Mapped by significant region TAS
FEN1 flap structure-specific endonuclease 1 Mapped by Literature SNP; Mapped by significant region TAS[8131753]
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) Mapped by significant region TAS
RAD21L1 RAD21-like 1 (S. pombe) Mapped by LD-proxy IEA
TRIP13 thyroid hormone receptor interactor 13 Mapped by significant region ISS
KAT5 K(lysine) acetyltransferase 5 Mapped by significant region IMP[10966108]
H2AFX H2A histone family, member X Mapped by significant region NAS[19234442]; TAS
PAPD7 PAP associated domain containing 7 Mapped by significant region NAS[10066793]
ATM ataxia telangiectasia mutated Mapped by CNV; Mapped by significant region TAS