ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0006919
Name activation of cysteine-type endopeptidase activity involved in apoptotic process
Type Biological Process
No. of Genes in ADHDgene  11
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 11)

Literature-origin genes (count: 1)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
SNCA synuclein, alpha (non A4 component of amyloid precursor) 4q21.3-q22 1(0/1/0)

Genes from other sources Help (count: 10)

Approved Symbol Approved Name Source Evidence[PMID]
BAD BCL2-associated agonist of cell death Mapped by significant region
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) Mapped by significant region TAS[10799503]
MAP3K5 mitogen-activated protein kinase kinase kinase 5 Mapped by LD-proxy; Mapped by significant region IDA[14761963]
TPD52L1 tumor protein D52-like 1 Mapped by significant region IDA[14761963]
PYCARD PYD and CARD domain containing Mapped by CNV NAS[12019269]
FADD Fas (TNFRSF6)-associated via death domain Mapped by significant region
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 Mapped by significant region IDA[15705586]
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 Mapped by significant region IDA[11911831]
EGLN3 egl nine homolog 3 (C. elegans) Mapped by LD-proxy; Mapped by literature SNP
RPS3 ribosomal protein S3 Mapped by significant region IDA[14988002]