ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0000165
Name MAPK cascade
Type biological process
No. of Genes in ADHDgene  10
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 10)

Literature-origin genes (count: 1)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ADRA2B adrenoceptor alpha 2B 2q11.1 1(1/0/0) IEA

Genes from other sources Help (count: 9)

Approved Symbol Approved Name Source Evidence[PMID]
MAPK3 mitogen-activated protein kinase 3 Mapped by CNV NAS; TAS
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy TAS
BRAP BRCA1 associated protein Mapped by LD-proxy IDA[14724641]
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) Mapped by PBA pathway IEP[12032188]
INS insulin Mapped by Literature SNP IDA[11278339]
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 Mapped by significant region IDA[8805275]
MEN1 multiple endocrine neoplasia I Mapped by significant region IDA[12226747]
IL18 interleukin 18 (interferon-gamma-inducing factor) Mapped by significant region IMP
MAP3K5 mitogen-activated protein kinase kinase kinase 5 Mapped by LD-proxy; Mapped by significant region IDA