ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005096
Name GTPase activator activity
Type Molecular Function
No. of Genes in ADHDgene  23
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 23)

Literature-origin genes (count: 3)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
TIAM2 T-cell lymphoma invasion and metastasis 2 6q25 1(0/0/1)
RGS18 regulator of G-protein signaling 18 1q31.2 1(0/1/0)
ARRB1 arrestin, beta 1 11q13 2(1/1/0) IMP[15611106]

Genes from other sources Help (count: 20)

Approved Symbol Approved Name Source Evidence[PMID]
RANBP1 RAN binding protein 1 Mapped by CNV
ARHGAP11A Rho GTPase activating protein 11A Mapped by CNV; Mapped by significant region
ARHGAP42 Rho GTPase activating protein 42 Mapped by significant region
CHN2 chimerin (chimaerin) 2 Mapped by CNV
ARHGAP11B Rho GTPase activating protein 11B Mapped by significant region
GAPVD1 GTPase activating protein and VPS9 domains 1 Mapped by significant region
RGS8 regulator of G-protein signaling 8 Mapped by significant region
RABGAP1 RAB GTPase activating protein 1 Mapped by significant region TAS[10202141]
ARHGAP32 Rho GTPase activating protein 32 Mapped by significant region
RGS3 regulator of G-protein signaling 3 Mapped by significant region
GARNL3 GTPase activating Rap/RanGAP domain-like 3 Mapped by significant region
ARHGAP20 Rho GTPase activating protein 20 Mapped by significant region
ELMOD1 ELMO/CED-12 domain containing 1 Mapped by significant region IDA[17452337]
SIPA1 signal-induced proliferation-associated 1 Mapped by significant region TAS[9346962]
RGS16 regulator of G-protein signaling 16 Mapped by significant region
ARHGAP18 Rho GTPase activating protein 18 Mapped by CNV; Mapped by significant region
RIN1 Ras and Rab interactor 1 Mapped by significant region
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 Mapped by significant region
ARHGAP19 Rho GTPase activating protein 19 Mapped by LD-proxy; Mapped by literature SNP
FAM13A family with sequence similarity 13, member A Mapped by CNV