ADHDgene Database

Gene Report

Basic Info

Approved Symbol	RGS3
Symbol Alias	C2PA, FLJ20370, PDZ-RGS3
Approved Name	regulator of G-protein signaling 3
Previous Name	regulator of G-protein signalling 3
Location	9q32
Position	chr9:116207011-116360018, +
External Links	HGNC: 9999 Entrez Gene: 5998 Ensembl: ENSG00000138835 UCSC: uc004bhq.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
9q31.1-33.1	chr9:102600000-122500000	1 (1/0/0)

Gene related GO terms (count: 9)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	Biological Process	TAS[9858594]	5
GO:0038032	termination of G-protein coupled receptor signaling pathway	Biological Process		9
GO:0043547	positive regulation of GTPase activity	Biological Process	TAS[9858594]	10
GO:0005634	nucleus	Cellular Component		770
GO:0005737	cytoplasm	Cellular Component		690
GO:0005829	cytosol	Cellular Component	TAS[9858594]	447
GO:0005886	plasma membrane	Cellular Component		772
GO:0000188	inactivation of MAPK activity	Biological Process	TAS[8602223]	3
GO:0005096	GTPase activator activity	Molecular Function		23

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04360	Axon guidance	25	Axon guidance represents a key stage in the formation of neu...... Axon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are read by growth cone receptors, and signal transduction pathways downstream of these receptors converge onto the Rho GTPases to elicit changes in cytoskeletal organization that determine which way the growth cone will turn. More...

Genes shared at least 5 GO terms with RGS3 (count: 3)

Gene Symbol	Pathway Count	Pathway List
RGS16	6	regulation of G-protein coupled receptor protein signaling pathway; termination of G-protein coupled receptor signaling pathway; positive regulation of GTPase activity; cytoplasm; plasma membrane; GTPase activator activity;
ARRB1	6	positive regulation of GTPase activity; nucleus; cytoplasm; cytosol; plasma membrane; GTPase activator activity;
RGS8	5	termination of G-protein coupled receptor signaling pathway; positive regulation of GTPase activity; cytoplasm; plasma membrane; GTPase activator activity;

Genes shared at least 2 KEGG pathways with RGS3 (count: 0)

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Region: chr9:116207011..116360018 View in gBrowse