ADHDgene Database

Gene Report

Basic Info

Approved Symbol	RGS3
Symbol Alias	C2PA, FLJ20370, PDZ-RGS3
Approved Name	regulator of G-protein signaling 3
Previous Name	"regulator of G-protein signalling 3"
Location	9q32
Position	chr9:116207011-116360018, 1
External Links	HGNC: 9999 Entrez Gene: 5998 Ensembl: ENSG00000138835 UCSC: uc004bhq.4
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
9q31.1-33.1	chr9:102600000-122500000	1 (1/0/0)

Gene related GO terms (count: 9)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0043547	positive regulation of GTPase activity	biological process	IBA; TAS[9858594]	12
GO:0038032	termination of G-protein coupled receptor signaling pathway	biological process	IEA	11
GO:0005829	cytosol	cellular component	TAS[9858594]	485
GO:0005096	GTPase activator activity	molecular function	IBA	28
GO:0005634	nucleus	cellular component	IEA	877
GO:0005737	cytoplasm	cellular component	IBA	781
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	biological process	TAS[9858594]	6
GO:0000188	inactivation of MAPK activity	biological process	TAS[8602223]	3
GO:0005886	plasma membrane	cellular component	IBA	839

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04360	Axon guidance	26

Genes shared at least 5 GO terms with RGS3 (count: 5)

Gene Symbol	Pathway Count	Pathway List
AXIN1	7	positive regulation of GTPase activity; termination of G-protein coupled receptor signaling pathway; cytosol; GTPase activator activity; nucleus; cytoplasm; plasma membrane;
ARRB1	6	positive regulation of GTPase activity; cytosol; GTPase activator activity; nucleus; cytoplasm; plasma membrane;
RGS16	6	positive regulation of GTPase activity; termination of G-protein coupled receptor signaling pathway; GTPase activator activity; cytoplasm; regulation of G-protein coupled receptor protein signaling pathway; plasma membrane;
RGS11	6	positive regulation of GTPase activity; termination of G-protein coupled receptor signaling pathway; GTPase activator activity; cytoplasm; regulation of G-protein coupled receptor protein signaling pathway; plasma membrane;
RGS8	5	positive regulation of GTPase activity; termination of G-protein coupled receptor signaling pathway; GTPase activator activity; cytoplasm; plasma membrane;

Genes shared at least 2 KEGG pathways with RGS3 (count: 0)

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Region: chr9:116207011..116360018 View in gBrowse