ADHDgene Database

Gene Report

Basic Info

Approved Symbol	RGS18
Symbol Alias	RGS13
Approved Name	regulator of G-protein signaling 18
Previous Name	regulator of G-protein signalling 18
Location	1q31.2
Position	chr1:192127587-192154945, +
External Links	HGNC: 14261 Entrez Gene: 64407 Ensembl: ENSG00000150681 UCSC: uc001gsg.2
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Hinney, A., 2011	This GWAS in a small group of clinically ascertained young German patients with ADHD and population-based controls did not reveal genome-wide significant findings. Replication attempts in further German and international samples did also not lead to a P-value(s) below 5E-08.	Non-significant

Gene related SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs650957	Chr1:191429227(Fwd)		1(0/1/0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 5)

ID	Name	Type	No. of Genes in ADHDgene
GO:0005096	GTPase activator activity	Molecular Function	23
GO:0005886	plasma membrane	Cellular Component	772
GO:0005737	cytoplasm	Cellular Component	690
GO:0007186	G-protein coupled receptor signaling pathway	Biological Process	72
GO:0038032	termination of G-protein coupled receptor signaling pathway	Biological Process	9

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with RGS18 (count: 0)

Genes shared at least 2 KEGG pathways with RGS18 (count: 0)

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Region: chr1:192127587..192154945 View in gBrowse