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- Data Summary
GO Report
Basic Info
| ID | GO:0000165 |
|---|---|
| Name | MAPK cascade |
| Type | Biological Process |
| No. of Genes in ADHDgene | 10 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 10)
Literature-origin genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| ADRA2B | adrenergic, alpha-2B-, receptor | 2q11.1 | 1(1/0/0) |
Genes from other sources (count: 9)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| MAPK3 | mitogen-activated protein kinase 3 | Mapped by CNV | |
| MAPK1 | mitogen-activated protein kinase 1 | Mapped by LD-proxy | |
| BRAP | BRCA1 associated protein | Mapped by LD-proxy | IDA[14724641] |
| INS | insulin | Mapped by literature SNP | IDA[11278339] |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | Mapped by significant region | IDA[8805275] |
| CCR5 | chemokine (C-C motif) receptor 5 | Mapped by PBA pathway | IEP[12032188] |
| MEN1 | multiple endocrine neoplasia I | Mapped by significant region | IDA[12226747] |
| IL18 | interleukin 18 (interferon-gamma-inducing factor) | Mapped by significant region | |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | Mapped by LD-proxy; Mapped by significant region |