ADHDgene Database

Gene Report

Basic Info

Approved Symbol	LYPLA1
Symbol Alias	LPL1
Approved Name	lysophospholipase I
Location	8q11.23-q12.1
Position	chr8:54958938-55014577, -
External Links	HGNC: 6737 Entrez Gene: 10434 Ensembl: ENSG00000120992 UCSC: uc003xry.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 10)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0004091	carboxylesterase activity	Molecular Function		40
GO:0016298	lipase activity	Molecular Function		49

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0004622	lysophospholipase activity	Molecular Function	TAS[10064899]	5
GO:0005739	mitochondrion	Cellular Component		183
GO:0005829	cytosol	Cellular Component		447
GO:0006631	fatty acid metabolic process	Biological Process		15
GO:0050999	regulation of nitric-oxide synthase activity	Biological Process		5
GO:0008474	palmitoyl-(protein) hydrolase activity	Molecular Function		1
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0046209	nitric oxide metabolic process	Biological Process		4

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa00564	Glycerophospholipid metabolism	22

Genes shared at least 5 GO terms with LYPLA1 (count: 4)

Gene Symbol	Pathway Count	Pathway List
PLA2G4B	5	lysophospholipase activity; cytosol; carboxylesterase activity; lipase activity; small molecule metabolic process;
PNPLA8	5	lysophospholipase activity; fatty acid metabolic process; carboxylesterase activity; lipase activity; small molecule metabolic process;
PLA2G6	5	mitochondrion; cytosol; carboxylesterase activity; lipase activity; small molecule metabolic process;
PTS	5	mitochondrion; cytosol; regulation of nitric-oxide synthase activity; small molecule metabolic process; nitric oxide metabolic process;

Genes shared at least 2 KEGG pathways with LYPLA1 (count: 0)

View in gBrowse

Region: chr8:54958938..55014577 View in gBrowse