ADHDgene Database

Gene Report

Basic Info

Approved Symbol	AMBP
Previous Symbol	ITI, ITIL
Symbol Alias	UTI, HCP, EDC1, HI30, IATIL, ITILC
Approved Name	alpha-1-microglobulin/bikunin precursor
Name Alias	growth-inhibiting protein 19, "uristatin", "complex-forming glycoprotein heterogeneous in charge", "bikunin", "inter-alpha-trypsin inhibitor light chain", "protein HC", "uronic-acid-rich protein", "trypstatin"
Location	9q32-q33
Position	chr9:116822407-116840752, -
External Links	HGNC: 453 Entrez Gene: 259 Ensembl: ENSG00000106927 UCSC: uc004bie.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
9q31.1-33.1	chr9:102600000-122500000	1 (1/0/0)

Gene related GO terms (count: 20)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0004867	serine-type endopeptidase inhibitor activity	Molecular Function	TAS[12817471]	10
GO:0005886	plasma membrane	Cellular Component	IDA[12817471]	772
GO:0007155	cell adhesion	Biological Process	NAS[9570066]	86
GO:0005576	extracellular region	Cellular Component	NAS[11877257]	240
GO:0005615	extracellular space	Cellular Component		126
GO:0018298	protein-chromophore linkage	Biological Process		1
GO:0019048	virus-host interaction	Biological Process		54
GO:0007565	female pregnancy	Biological Process	NAS[10097787]	14
GO:0009986	cell surface	Cellular Component		70
GO:0020037	heme binding	Molecular Function	IDA[11877257]	23
GO:0030163	protein catabolic process	Biological Process		5
GO:0019855	calcium channel inhibitor activity	Molecular Function	NAS[12817471]	2
GO:0019862	IgA binding	Molecular Function	IDA[11877257]	1
GO:0042167	heme catabolic process	Biological Process	NAS[11877257]	2
GO:0036094	small molecule binding	Molecular Function		1
GO:0043231	intracellular membrane-bounded organelle	Cellular Component		62
GO:0042803	protein homodimerization activity	Molecular Function	IPI[11883904]	113
GO:0046904	calcium oxalate binding	Molecular Function	NAS[14516400]	1
GO:0046329	negative regulation of JNK cascade	Biological Process	TAS[12817471]	6
GO:0050777	negative regulation of immune response	Biological Process	NAS[10097787]	1

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with AMBP (count: 3)

Gene Symbol	Pathway Count	Pathway List
ACHE	6	plasma membrane; cell adhesion; extracellular region; extracellular space; cell surface; protein homodimerization activity;
GHR	5	plasma membrane; extracellular region; extracellular space; cell surface; protein homodimerization activity;
SCARB1	5	plasma membrane; cell adhesion; virus-host interaction; cell surface; protein homodimerization activity;

Genes shared at least 2 KEGG pathways with AMBP (count: 0)

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Region: chr9:116822407..116840752 View in gBrowse