ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs998424 dbSNP Ensembl
Location chr16:55731946(Fwd)
Variant Alleles G/A
Ancestral Allele G
Functional Annotation downstream_gene_variant; intron_variant; upstream_gene_variant.
Consequence to Transcript downstream_gene_variant(ENST00000568529)
intron_variant(ENST00000219833; ENST00000379906; ENST00000414754; ENST00000561820; ENST00000566163; ENST00000567238; ENST00000568943)
upstream_gene_variant(ENST00000574918)
No. of Studies 7 (significant: 2; non-significant: 5; trend: 0)
Source Literature-origin

SNP related studies (count: 7)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Sengupta, S. M., 2012 C/T P-value=0.08, Z statistic (allele 1)=1.76 P-value=0.08, Z statistic (allele 1)=1.76 No significant association was found in this study. No significant association was found in this study. Non-significant
Kim JW, 2008 X2=0.943, P-value=0.331, OR=1.1 X2=0.943, P-value=0.331, OR=1.1 not associated with ADHD not associated with ADHD Non-significant
Forero DA, 2009 C/T Not significant for the total samples. Not significant for the total samples. Non-significant
Ilott NE, 2010 QTDT AT P-value=0.07, X2=3.3, df=1, QTDT AW P-val...... QTDT AT P-value=0.07, X2=3.3, df=1, QTDT AW P-value=0.04, X2=4.42, df=1 at age 2; QTDT AT P-value=0.59, X2=0.83, df=1, QTDT AW P-value=0.07, X2=3.22, df=1 at age 3 More... modest, nominally significant associations in the AW test at...... modest, nominally significant associations in the AW test at age 2 More... Significant
De Luca V, 2004 (a) G/A A TDT P-value=0.647, ANOVA P-value=0.941, FBAT P-value=0.48 fo...... TDT P-value=0.647, ANOVA P-value=0.941, FBAT P-value=0.48 for Wender, FBAT P-value=0.25 for BDD activation, FBAT P-value=0.17 for BDD attention, FBAT P-value=0.26 for BDD total More... There was no preferential transmission of either allele There was no preferential transmission of either allele Non-significant
Bobb AJ, 2005 allelic TDT P-value=0.91, OR=0.98 in case-control analysis; ...... allelic TDT P-value=0.91, OR=0.98 in case-control analysis; allelic TDT P-value=0.009, RR=1.96 in family-based analysis More... there was preferential transmission of the C allele to ADHD ...... there was preferential transmission of the C allele to ADHD probands More... Significant
Xu X, 2005(a) allelic X2 statistic P-value=0.066, OR=1.2 allelic X2 statistic P-value=0.066, OR=1.2 no evidence for association no evidence for association Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 0)


SNPs in LD with rs998424 (count: 0) View in gBrowse (chr16:55731946..55731946 )