ADHDgene Database

SNP Report

Basic Info

Name	rs6313 dbSNP Ensembl
Location	chr13:47469940(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	intron_variant; synonymous_variant.
Consequence to Transcript	intron_variant(ENST00000543956) synonymous_variant(ENST00000378688; ENST00000542664)
No. of Studies	4 (significant: 0; non-significant: 4; trend: 0)
Source	Literature-origin

SNP related studies (count: 4)

Reference	Allele Change	Statistical Values	Author Comments	Result of Statistical Analysis
Brookes K, 2006	A/G	UNPHASED TDT P-value=0.159; WHAP TDT P-value=0.271 UNPHASED TDT P-value=0.159; WHAP TDT P-value=0.271	no significant association was observed no significant association was observed	Non-significant
Gizer IR, 2009		Meta-analysis model: Fixed: OR=0.96, 95% CI=0.86-1.06, two-t...... Meta-analysis model: Fixed: OR=0.96, 95% CI=0.86-1.06, two-tailed P-value=0.379; Q-statistic: P-value=0.644, I²=0 More...	no evidence to suggest an association between this polymorph...... no evidence to suggest an association between this polymorphisms and ADHD More...	Non-significant
Bobb AJ, 2005		allelic TDT P-value=0.82, OR=1.04 in case-control analysis; ...... allelic TDT P-value=0.82, OR=1.04 in case-control analysis; allelic TDT P-value=0.83, RR=1.05 in family-based analysis More...	non-significant association non-significant association	Non-significant
Heiser P, 2007	C/T	allelic PDT P-value=0.40 allelic PDT P-value=0.40	showed no statistically significant preferential transmissio...... showed no statistically significant preferential transmission of any allele More...	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
HTR2A	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled	13q14-q21	13(7/6/0)

SNPs in LD with rs6313 (count: 23) View in gBrowse (chr13:47439371..47523624 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.