ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

SNP Report

Basic Info

Name	rs2519152 dbSNP Ensembl
Location	Chr9:136509634(Fwd)
Variant Alleles	T/C
Ancestral Allele	T
Functional Annotation	downstream_gene_variant; intron_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000263611) intron_variant(ENST00000393056)
No. of Studies	6 (significant: 2; non-significant: 4; trend: 0)
Source	Literature-origin

SNP related studies (count: 6)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Gizer IR, 2009			Meta-analysis model: Random: OR=1.12, 95% CI=0.80-1.55, P-va...... Meta-analysis model: Random: OR=1.12, 95% CI=0.80-1.55, P-value=0.206; Q-statistic: P-value=0.004, I²=71 More...	The results of the meta-analysis were statistically mixed. D...... The results of the meta-analysis were statistically mixed. Due to the magnitude of the observed heterogeneity, it is difficult to draw definitive conclusions regarding the association between childhood ADHD and the polymorphisms/gene. More...	Non-significant
Hawi, Z., 2012	T:C	C	P-value=0.2893, X²=1.12, OR=1.15, 95% CI=0.88-1.4...... P-value=0.2893, X²=1.12, OR=1.15, 95% CI=0.88-1.49 More...	The marker did not show significant association with ADHD. The marker did not show significant association with ADHD.	Non-significant
Bhaduri N, 2006 (b)			allelic HHRR P-value=0.48, X²=0.49, RR=1.10 (for ...... allelic HHRR P-value=0.48, X²=0.49, RR=1.10 (for A1); allelic TDT P-value=0.42, X²=0.64, RR=0.9 (for A2) More...	HHRR analysis showed lack of preferential transmission in AD...... HHRR analysis showed lack of preferential transmission in ADHD probands and TDT revealed a slight increase in transmission of allele 1 More...	Non-significant
Carpentier, P. J., 2012	C>T	C	genotypic P-value=0.008, adj OR=1.73, 95%CI=1.15-2.59; P-val...... genotypic P-value=0.008, adj OR=1.73, 95%CI=1.15-2.59; P-value=0.48, adj OR=1.13, 95%CI=0.80-1.60 with gender as the covariate More...	After the Bonferroni correction, a significant association w...... After the Bonferroni correction, a significant association with disease was found for the DBH (OR 1.73;CI1.15-2.59; P=0.008)and the OPRM1 (OR 1.71;CI1.17-2.50; P=0.006) risk genotypes. The covariate Gender had no significant effect. More...	Significant
Nyman ES, 2007			No available information. No available information.	No evidence of association was seen. No evidence of association was seen.	Non-significant
Bhaduri N, 2010	A:G		allelic frequencies P-value=0.6, X²=0.27; genotyp...... allelic frequencies P-value=0.6, X²=0.27; genotypic frequencies P-value=0.65, X²=0.86; HHRR P-value=0.25, OR=0.74, X²=1.34, TDT P-value=0.22, RR=0.71, X²=1.54 for overall transmission; HHRR P-value=0.03, OR=0.46, X²=4.66, TDT P-value=0.02, RR=0.4, X²=5.31 for paternal transmission; HHRR P-value=0.58, OR=1.23, X²=0.31, TDT P-value=0.55, RR=1.27, X²=0.36 for maternal transmission More...	showed a statistically significant over-transmission of the ...... showed a statistically significant over-transmission of the ¡®G¡¯ allele from father to probands More...	Significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Genes from other sources (count: 0)

SNPs in LD with rs2519152 (count: 0) View in gBrowse (chr9:136509634..136509634 )