ADHDgene Database

SNP Report

Basic Info

Name	rs12653825 dbSNP Ensembl
Location	Chr5:159383271(Fwd)
Variant Alleles	C/T
Ancestral Allele	T
Functional Annotation	intron_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000306675) upstream_gene_variant(ENST00000505218)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Hawi, Z., 2012	C:T	C	P-value=0.2031, X²=1.62, OR=1.2, 95% CI=1.19-1.58 P-value=0.2031, X²=1.62, OR=1.2, 95% CI=1.19-1.58	The marker did not show significant association with ADHD. The marker did not show significant association with ADHD.	Non-significant

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
ADRA1B	adrenergic, alpha-1B-, receptor	5q33.3	2(1/1/0)

Approved Symbol	Approved Name	Location
GAPDHP40	glyceraldehyde 3 phosphate dehydrogenase pseudogene 40	5q33.3

SNPs in LD with rs12653825 (count: 4) View in gBrowse (chr5:159360485..159383271 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs6888306	intron_variant	1(1/0/0)	0.851[YRI]
rs7737796	intron_variant	1(1/0/0)	0.953[GIH]
rs6892282	intron_variant	1(0/1/0)	0.82[GIH]