ADHDgene Database

SNP Report

Basic Info

Name	rs6888306 dbSNP Ensembl
Location	Chr5:159367114(Fwd)
Variant Alleles	C/T
Ancestral Allele	T
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000306675)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Hawi, Z., 2012	C:T	C	P-value=0.0147, X²=5.95, OR=1.46, 95% CI=1.07-1....... P-value=0.0147, X²=5.95, OR=1.46, 95% CI=1.07-1.97 More...	Nominal associations between ADHD and the marker was observe...... Nominal associations between ADHD and the marker was observed. However, the association did not remain significant after adjusting the p values using 10,000 permutations. More...	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
ADRA1B	adrenergic, alpha-1B-, receptor	5q33.3	2(1/1/0)

SNPs in LD with rs6888306 (count: 4) View in gBrowse (chr5:159356484..159383271 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.


rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]
rs12653825	intron_variant; upstream_gene_variant	1(0/1/0)	0.851[YRI]

rs_ID	Functional Annotation	r²[population]
rs3844071	intron_variant; upstream_gene_variant	0.847[YRI]
rs1474190	intron_variant	0.907[CHB]; 0.901[CHD]; 0.95[JPT]
rs13171967	intron_variant; nc_transcript_variant; non_coding_exon_variant	0.809[CEU]; 0.968[GIH]; 0.816[MKK]; 0.884[TSI]