ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs11568324 dbSNP Ensembl
Location chr16:55726058(Fwd)
Variant Alleles C/T
Ancestral Allele C
Functional Annotation intron_variant.
Consequence to Transcript intron_variant(ENST00000219833; ENST00000379906; ENST00000414754; ENST00000561820; ENST00000566163; ENST00000567238; ENST00000568529; ENST00000568943)
No. of Studies 5 (significant: 4; non-significant: 1; trend: 0)
Source Literature-origin

SNP related studies (count: 5)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Brookes K, 2006 A/G UNPHASED TDT P-value=0.0153 UNPHASED TDT P-value=0.0153 significant association was observed in UNPHASED analysis significant association was observed in UNPHASED analysis Significant
Sengupta, S. M., 2012 C/T P-value=0.56, Z statistic (allele 1)=0.58 P-value=0.56, Z statistic (allele 1)=0.58 No significant association was found in this study. No significant association was found in this study. Non-significant
Xu X, 2008(b) T/C TDT P-value=0.004, OR=0.26 in ST1; TDT P-value=0.22, OR=0.54...... TDT P-value=0.004, OR=0.26 in ST1; TDT P-value=0.22, OR=0.54 in ST2; TDT P-value=0.03, OR=0.31 in MGH; TDT P-value=0.16, OR=0.33 in Dublin; TDT P-value=0.00008, OR=0.34 in TOTAL; P-value=0.003, OR=0.21 in ST1; P-value=0.3, OR=0.59 in ST2, P-value=0.12, OR=0.32 in Dublin; P-value=0.007, OR=0.34 in Total, for allele counts More... the overall evidence of association was significant across a...... the overall evidence of association was significant across all four datasets More... Significant
Ilott NE, 2010 QTDT AT P-value=0.04, X2=4.38, df=1, at age 2; QT...... QTDT AT P-value=0.04, X2=4.38, df=1, at age 2; QTDT AT P-value=0.13, X2=0.58, df=1, at age 3 More... modest, nominally significant associations in the AT test at...... modest, nominally significant associations in the AT test at age 2 More... Significant
Kim JW, 2008 X2=4.765, P-value=0.029, OR=3.25; X2=1...... X2=4.765, P-value=0.029, OR=3.25; X2=10.3, P-value=0.0013, OR=3.37 in the combined study More... shows positive associations shows positive associations Significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 0)


SNPs in LD with rs11568324 (count: 0) View in gBrowse (chr16:55726058..55726058 )