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KEGG Pathway Report
Basic Info
| ID | hsa00260 |
|---|---|
| Name | Glycine, serine and threonine metabolism |
| Description | Serine is derived from 3-phospho-D-glycerate, an intermediate of glycolysis [MD:M00020], and glycine is derived from serine. Threonine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, threonine is derived from aspartate [MD:M00018]. |
| No. of Genes in ADHDgene | 6 |
| Source | Pathway by Database Search |
Pathway related genes in ADHDgene (count: 6)
Literature-origin genes (count: 2)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
|---|---|---|---|
| MAOB | monoamine oxidase B | Xp11.4-p11.3 | 6(2/4/0) |
| MAOA | monoamine oxidase A | Xp11.4-p11.3 | 20(13/7/0) |
Genes from other sources (count: 4)
| Approved Symbol | Approved Name | Location | Source |
|---|---|---|---|
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) | 12q12-q14 | Mapped by CNV |
| AGXT2 | alanine--glyoxylate aminotransferase 2 | 5p13 | Mapped by significant region |
| SARDH | sarcosine dehydrogenase | 9q33-q34 | Mapped by LD-proxy |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) | 17p11.2 | Mapped by significant region |