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- Data Summary
GO Report
Basic Info
| ID | GO:0005923 |
|---|---|
| Name | tight junction |
| Type | Cellular Component |
| No. of Genes in ADHDgene | 15 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 15)
Literature-origin genes (count: 3)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 7q21 | 1(0/0/1) | IDA[10760291] |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 10q21 | 1(0/1/0) | IDA[14757759] |
| LIN7C | lin-7 homolog C (C. elegans) | 11p14 | 1(1/0/0) |
Genes from other sources (count: 12)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | Mapped by PBA pathway | |
| TJP1 | tight junction protein 1 (zona occludens 1) | Mapped by CNV; Mapped by significant region | IDA[14757759] |
| AMOTL1 | angiomotin like 1 | Mapped by significant region | IDA[16019084] |
| APC | adenomatous polyposis coli | Mapped by LD-proxy; Mapped by PBA pathway | IDA[18502210] |
| JAM3 | junctional adhesion molecule 3 | Mapped by significant region | |
| CLDN5 | claudin 5 | Mapped by CNV | |
| CLMP | CXADR-like membrane protein | Mapped by significant region | |
| CLDN25 | claudin 25 | Mapped by significant region | |
| CCND1 | cyclin D1 | Mapped by significant region | |
| AMICA1 | adhesion molecule, interacts with CXADR antigen 1 | Mapped by significant region | IDA[15800062] |
| ESAM | endothelial cell adhesion molecule | Mapped by significant region | |
| TGFBR1 | transforming growth factor, beta receptor 1 | Mapped by significant region | IDA[15761148] |