ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0005200
Name	structural constituent of cytoskeleton
Type	Molecular Function
No. of Genes in ADHDgene	14
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 14)

Literature-origin genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
ANK3	ankyrin 3, node of Ranvier (ankyrin G)	10q21	1(0/1/0)	IMP[17620337]
CTNNA2	catenin (cadherin-associated protein), alpha 2	2p12-p11.1	2(1/1/0)	NAS[8432524]

Genes from other sources (count: 12)

Approved Symbol	Approved Name	Source	Evidence[PMID]
SPTBN2	spectrin, beta, non-erythrocytic 2	Mapped by significant region	TAS[9826670]
MAPT	microtubule-associated protein tau	Mapped by LD-proxy; Mapped by PBA pathway	TAS[2498079]
SORBS3	sorbin and SH3 domain containing 3	Mapped by PBA pathway	TAS[9885244]
TUBG1	tubulin, gamma 1	Mapped by PBA pathway	TAS[1904010]
EPB41L4B	erythrocyte membrane protein band 4.1 like 4B	Mapped by significant region	TAS[10783258]
ACTL7B	actin-like 7B	Mapped by significant region	TAS[10373328]
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	Mapped by significant region	TAS[9230079]
DES	desmin	Mapped by significant region	TAS[9736733]
ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	Mapped by significant region	TAS[9230079]
ACTL7A	actin-like 7A	Mapped by significant region	TAS[10373328]
CYLC2	cylicin, basic protein of sperm head cytoskeleton 2	Mapped by significant region
TUBGCP4	tubulin, gamma complex associated protein 4	Mapped by LD-proxy	NAS[10562286]