ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0051968
Name	positive regulation of synaptic transmission, glutamatergic
Type	Biological Process
No. of Genes in ADHDgene	8
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 8)

Literature-origin genes (count: 4)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
DRD1	dopamine receptor D1	5q34-q35	8(5/3/0)
NRXN1	neurexin 1	2p16.3	1(0/1/0)
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	9q22.1	1(1/0/0)
OXTR	oxytocin receptor	3p25	1(0/1/0)

Genes from other sources (count: 4)

Approved Symbol	Approved Name	Source	Evidence[PMID]
NLGN1	neuroligin 1	Mapped by CNV
GLUL	glutamate-ammonia ligase	Mapped by significant region
ADORA2A	adenosine A2a receptor	Mapped by CNV
TNR	tenascin R (restrictin, janusin)	Mapped by significant region