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- Data Summary
GO Report
Basic Info
| ID | GO:0042136 |
|---|---|
| Name | neurotransmitter biosynthetic process |
| Type | Biological Process |
| No. of Genes in ADHDgene | 6 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 6)
Literature-origin genes (count: 5)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| TH | tyrosine hydroxylase | 11p15.5 | 7(2/5/0) | |
| COMT | catechol-O-methyltransferase | 22q11.21 | 25(5/20/0) | |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 5p15.3 | 68(42/25/1) | |
| MAOA | monoamine oxidase A | Xp11.4-p11.3 | 20(13/7/0) | |
| NOS1 | nitric oxide synthase 1 (neuronal) | 12q14-qter | 1(1/0/0) | TAS[7545544] |
Genes from other sources (count: 1)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| ACHE | acetylcholinesterase | Mapped by PBA pathway |