ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0007218
Name	neuropeptide signaling pathway
Type	Biological Process
No. of Genes in ADHDgene	17
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 17)

Literature-origin genes (count: 4)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
SORCS3	sortilin-related VPS10 domain containing receptor 3	10q23-q25	1(0/0/1)	NAS[11499680]
SORCS1	sortilin-related VPS10 domain containing receptor 1	10q23-q25	1(0/0/1)	NAS[11499680]
LPHN3	latrophilin 3	4q13.1	4(3/0/1)
GPR125	G protein-coupled receptor 125	4p15.31	1(0/1/0)

Genes from other sources (count: 13)

Approved Symbol	Approved Name	Source	Evidence[PMID]
SCG5	secretogranin V (7B2 protein)	Mapped by CNV; Mapped by significant region
SORT1	sortilin 1	Mapped by CNV	IDA[9756851]
NPY	neuropeptide Y	Mapped by CNV; Mapped by significant region
NXPH4	neurexophilin 4	Mapped by CNV	NAS[9570794]
GPR144	G protein-coupled receptor 144	Mapped by significant region
BAI3	brain-specific angiogenesis inhibitor 3	Mapped by significant region
NMS	neuromedin S	Mapped by CNV
CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	Mapped by CNV
GAL	galanin prepropeptide	Mapped by CNV; Mapped by significant region
NPVF	neuropeptide VF precursor	Mapped by CNV; Mapped by significant region	NAS[11025660]
GRP	gastrin-releasing peptide	Mapped by significant region	IDA[8756537]
NMU	neuromedin U	Mapped by LD-proxy
PKD1L2	polycystic kidney disease 1-like 2	Mapped by significant region