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- Data Summary
GO Report
Basic Info
| ID | GO:0051967 |
|---|---|
| Name | negative regulation of synaptic transmission, glutamatergic |
| Type | Biological Process |
| No. of Genes in ADHDgene | 5 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 5)
Literature-origin genes (count: 4)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A | 13q14-q21 | 12(6/6/0) | |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B | 6q13 | 13(5/8/0) | |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | 21q22 | 1(0/0/1) | |
| DRD2 | dopamine receptor D2 | 11q22-q23 | 10(3/7/0) |
Genes from other sources (count: 1)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) | Mapped by PBA pathway |