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- Data Summary
GO Report
Basic Info
| ID | GO:0006469 |
|---|---|
| Name | negative regulation of protein kinase activity |
| Type | Biological Process |
| No. of Genes in ADHDgene | 13 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 13)
Literature-origin genes (count: 3)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| PPP1R1B | protein phosphatase 1, regulatory (inhibitor) subunit 1B | 17 | 1(0/1/0) | TAS[10604473] |
| PPM1F | protein phosphatase, Mg2+/Mn2+ dependent, 1F | 22q11.22 | 1(0/0/1) | IDA[11864573] |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 7q35-q36 | 1(0/0/1) | IDA[17255938] |
Genes from other sources (count: 10)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| GADD45G | growth arrest and DNA-damage-inducible, gamma | Mapped by significant region | |
| CAV3 | caveolin 3 | Mapped by LD-proxy; Mapped by literature SNP | |
| NF2 | neurofibromin 2 (merlin) | Mapped by PBA pathway | |
| THY1 | Thy-1 cell surface antigen | Mapped by significant region | |
| IL6 | interleukin 6 (interferon, beta 2) | Mapped by significant region | |
| ILK | integrin-linked kinase | Mapped by CNV | |
| ADORA2A | adenosine A2a receptor | Mapped by CNV | |
| CRIPAK | cysteine-rich PAK1 inhibitor | Mapped by PBA pathway | IDA[16278681] |
| GSTP1 | glutathione S-transferase pi 1 | Mapped by significant region | IDA[16636664] |
| PYDC1 | PYD (pyrin domain) containing 1 | Mapped by CNV | IDA[12656673] |