ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0070371
Name ERK1 and ERK2 cascade
Type biological process
No. of Genes in ADHDgene  7
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 7)

Literature-origin genes (count: 4)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Xq23 5(2/3/0) IMP[19057895]
FGF10 fibroblast growth factor 10 5p13-p12 1(0/1/0) IDA[17959718]
OXTR oxytocin receptor 3p25 1(0/1/0) IEA
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 13q14-q21 13(7/6/0) IMP[19057895]

Genes from other sources Help (count: 3)

Approved Symbol Approved Name Source Evidence[PMID]
PTGER4 prostaglandin E receptor 4 (subtype EP4) Mapped by significant region ISS
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy IDA[16314496]; TAS
MED1 mediator complex subunit 1 Mapped by LD-proxy; Mapped by PBA pathway IDA[18391015]