ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0051967
Name negative regulation of synaptic transmission, glutamatergic
Type biological process
No. of Genes in ADHDgene  5
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 5)

Literature-origin genes (count: 4)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
GRIK1 glutamate receptor, ionotropic, kainate 1 21q22 1(0/0/1) IEA
DRD2 dopamine receptor D2 11q22-q23 10(3/7/0) ISS
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 13q14-q21 13(7/6/0) IEA
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 6q13 14(5/9/0) IEA

Genes from other sources Help (count: 1)

Approved Symbol Approved Name Source Evidence[PMID]
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) Mapped by PBA pathway IEA