ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0007189
Name	adenylate cyclase-activating G-protein coupled receptor signaling pathway
Type	Biological Process
No. of Genes in ADHDgene	8
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 8)

Literature-origin genes (count: 6)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
GNAL	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type	18p11.22-p11.21	1(1/0/0)
ADRB3	adrenergic, beta-3-, receptor	8p12	2(0/2/0)
ADRB2	adrenergic, beta-2-, receptor, surface	5q31-q32	2(1/1/0)
DRD1	dopamine receptor D1	5q34-q35	8(5/3/0)	IDA[2144334]
ADRB1	adrenergic, beta-1-, receptor	10q24-q26	2(0/2/0)
DRD5	dopamine receptor D5	4p16.1	22(14/6/2)	IDA[11500503]

Genes from other sources (count: 2)

Approved Symbol	Approved Name	Source	Evidence[PMID]
ADORA2A	adenosine A2a receptor	Mapped by CNV
ADCY4	adenylate cyclase 4	Mapped by significant region