ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0070371
Name	ERK1 and ERK2 cascade
Type	Biological Process
No. of Genes in ADHDgene	7
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 7)

Literature-origin genes (count: 4)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	Xq24	5(2/3/0)	IMP[19057895]
FGF10	fibroblast growth factor 10	5p13-p12	1(0/1/0)	IDA[17959718]
OXTR	oxytocin receptor	3p25	1(0/1/0)
HTR2A	5-hydroxytryptamine (serotonin) receptor 2A	13q14-q21	12(6/6/0)	IMP[19057895]

Genes from other sources (count: 3)

Approved Symbol	Approved Name	Source	Evidence[PMID]
MAPK1	mitogen-activated protein kinase 1	Mapped by LD-proxy	IDA[16314496]
MED1	mediator complex subunit 1	Mapped by LD-proxy; Mapped by PBA pathway	IDA[18391015]
PTGER4	prostaglandin E receptor 4 (subtype EP4)	Mapped by significant region